Hsp90 alpha Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Hsp90 alpha antibody, protein, ELISA kits.
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| Antigenic Specificity | Hsp90 alpha |
| Clone | [Hyb-K41009] |
| Host Species | Mouse |
| Reactive Species | human (Alpha specific), rat |
| Isotype | IgG2a |
| Format | streptavidin conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects 90kDa proteins corresponding to the molecular mass of Hsp90alpha. Scientific Background: HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of Hsp90, are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer.(2) From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. (3-6) Furthermore, Hsp90 is highly conserved between species; having 60% and 78% ami |
| Immunogen | n/a |
| Other Names | [Hsp86; Hsp89A; Hsp90A; Hsp90AA1; Hsp90Alpha; HSPC1; HSPCA; HSPCAL3], [HSP90AA1; HSP90AA1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; HSP90A; HSPC1; HSPCA; HSP 86; HSP86; LAP-2; LPS-associated protein 2] |
| Gene, Accession # | Gene ID: 3320, NCBI: NP_001017963.2, UniProt: P07900 |
| Catalog # | MBS800126 |
| Price | $450 |
| Order / More Info | Hsp90 alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nemoto, T. et al. (1997) J.Biol Chem. 272, 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266, 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem 278, 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem 59,157-186. 5. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 6. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 7. Pratt W, Toft D. (1997) Endocr Rev 18,306-360. 8. Pratt WB. (1998) Proc Soc Exptl Biol Med 217, 420-434. 9. Whitesell L, et al. (1994) Proc Natl Acad Sci USA 91, 8324-8328. 10. Nemoto, T. (1997) Biochem and Mol. Bio Intl. 42 (5), 881-889.1. Shipp, C., Watson, K., and Jones, G.L. (2011). Associations of HSP90 Client Proteins in Human Breast Cancer. Anticancer Research. 31 (6), 2095-2101.2. Xi, C., et. al. (2012). Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis. J Biol Chem. 287, 35646-35657. doi: 10.1074/jbc.M112.377481 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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