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Antigenic Specificity | DUSP8 (C-term), 456-487 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DUSP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-487 amino acids from the C-terminal region of human DUSP8. DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, |
Immunogen | n/a |
Other Names | [Dual specificity protein phosphatase 8; Dual specificity protein phosphatase hVH-5; DUSP8; C11orf81; VH5] |
Gene, Accession # | [DUSP8], Gene ID: 1850, NCBI: NP_004411.2, UniProt: Q13202 |
Catalog # | MBS9210079 |
Price | $165, $370 |
Order / More Info | DUSP8 (C-term), 456-487 Antibody from MYBIOSOURCE INC. |
Product Specific References | Berger, I.R., et al., Cancer Genet. Cytogenet. 159(2):155-159 (2005). Hink, R.L., et al., Genomics 8(3):305-312 (2003). Nesbit, M.A., et al., Genomics 42(2):284-294 (1997). Martell, K.J., et al., J. Neurochem. 65(4):1823-1833 (1995). |