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Antigenic Specificity | Caspase 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect Caspase 1 in human samples. Caspase-1 (also known as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis to yield large (20 kDa) and small (10 kDa) subunits. The active caspase-1 is a heterotetramer consisting of two large and two small subunits. To date the regulatory mechanism of caspase-1 activation and the role of caspase-1 in apoptosis are poorly understood. In THP-1 cells; a large proportion of the caspase-1 is present in the inactive proenzyme form. |
Immunogen | Immunogen: Mouse Recombinant Caspase 1 |
Other Names | [CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme], [Casp1; Casp1; ICE; Il1bc; Il1bc; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme] |
Gene, Accession # | Gene ID: 12362, NCBI: NP_033937.2, UniProt: P29452 |
Catalog # | MBS845520 |
Price | $150, $305 |
Order / More Info | Caspase 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |