Caspase 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionPolyclonal Antibody to detect Caspase 1 in human samples. Caspase-1 (also known as ICE) is a prototypical member of the caspase-family of cysteine proteases. Caspase-1 exists in cells as an inactive 45 kDa proenzyme. The pro-enzyme is matured by proteolysis to yield large (20 kDa) and small (10 kDa) subunits. The active caspase-1 is a heterotetramer consisting of two large and two small subunits. To date the regulatory mechanism of caspase-1 activation and the role of caspase-1 in apoptosis are poorly understood. In THP-1 cells; a large proportion of the caspase-1 is present in the inactive proenzyme form.
ImmunogenImmunogen: Mouse Recombinant Caspase 1
Other Names[CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme], [Casp1; Casp1; ICE; Il1bc; Il1bc; CASP-1; IL-1BC; ICE; IL-1 beta-converting enzyme]
Gene, Accession #Gene ID: 12362, NCBI: NP_033937.2, UniProt: P29452
Catalog #MBS845520
Price$150, $305
Order / More InfoCaspase 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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