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Antigenic Specificity | FOXO1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mg |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti FOXO1 antibody recognizes Forkhead box protein O1, also known as FOXO1, Forkhead box protein O1A or Forkhead in rhabdomyosarcoma. FOXO1 like other members of the forkhead protein family acts as a transcription factor by binding to DNA with its forkhead box protein domain. The subcellular activation and thereby the transcriptional activity of FOXO1 is regulated via AKT mediated phosphorylation while its levels are regulated via polyubiquitination. FOXO1 has been shown to play a role in various signaling pathways ranging from apoptosis, proliferation, oxidative stress, DNA damage to insulin signaling (Huang and Tindall 2007). The protein has also been proposed to act as a tumor suppressor (Fu and Tindall 2008, Xie et al.2012). |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 633-647 of human FOXO1 |
Other Names | [FOXO1], [FOXO1; FOXO1; FKH1; FKHR; FOXO1A; FKHR; FOXO1A] |
Gene, Accession # | [FOXO1], Gene ID: 2308, NCBI: Q12778.2, UniProt: Q12778 |
Catalog # | MBS225047 |
Price | $470 |
Order / More Info | FOXO1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |