NME2/nm23-H2/NDPK-B (Suppressor of Metastasis) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNME2/nm23-H2/NDPK-B (Suppressor of Metastasis)
Clone[CPTC-NME2-2]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG2a
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistology (Formalin-Fixed)
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DescriptionThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.
ImmunogenImmunogen: Recombinant full-length human NME2 protein Positive Control: HeLa, Jurkat Cells. Ubiquitously expressed in all tissues.
Other Names[C myc purine binding transcription factor PUF; C myc transcription factor; C-myc purine-binding transcription factor PUF; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; NDK B; NDKB; NDP kinase B; NDPK B; NDPKB; NM23 H2; nm23-H2; NM23B; NME/NM23 nucleoside diphosphate kinase 2; nme2; Non metastatic cells 2, protein (NM23B) expressed in; non-metastatic cells 2, protein (NM23) expressed in; Nucleoside diphosphate kinase B; Nucleotide diphosphate kinase B; PUF]
Gene, Accession #[NME2], Gene ID: 654364, NCBI: NP_001018146.1, UniProt: P22392
Catalog #MBS4380647
Price$190, $340, $340
Order / More InfoNME2/nm23-H2/NDPK-B (Suppressor of Metastasis) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesTong, Y., et al. 2015. Cancer Lett. 361: 207-21
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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