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Antigenic Specificity | LEF-1 (Phospho Ser42) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-LEF-1 (S42) Polyclonal Antibody detects endogenous levels of LEF-1 protein only when phosphorylated at S42. LEF1 (lymphoid enhancer binding factor 1) encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in LEF1 have been found in somatic sebaceous tumors. LEF1 has also been linked to other cancers, including androgen-independent prostate ca |
Immunogen | Immunogen: Synthesized peptide derived from human LEF-1 around the phosphorylation site of S42 |
Other Names | [Rabbit LEF-1 (phospho Ser42); LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha] |
Gene, Accession # | [LEF-1], Gene ID: 51176, NCBI: NP_001124185.1, UniProt: Q9UJU2 |
Catalog # | MBS9706133 |
Price | $130, $220, $325 |
Order / More Info | LEF-1 (Phospho Ser42) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |