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Antigenic Specificity | EPB41 (Phospho-Tyr660/418) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of EPB41 only when phosphorylated at tyrosine 660/418. Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. Inherited as an autosomal dominant, elliptocytosis results from mutation in any one of several genes encoding proteins of the red cell membrane skeleton. The form discussed here is the one found in the 1950s to be linked to Rh blood group and more recently shown to be caused by a defect in protein 4.1. 'Rh-unlinked' forms of elliptocytosis are caused by mutation in the alpha-spectrin gene, the beta-spectrin gene, or the band 3 gene.Conboy J.G., Proc. Natl. Acad. Sci. U.S.A. 83:9512-9516(1986).Tang T.K., Adv. Exp. Med |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R)derived from Human EPB41. |
Other Names | [E41P; EPB4.1; band 4.1; P4.1] |
Gene, Accession # | [EPB41], Gene ID: 2035, NCBI: NP_001159477.1, UniProt: P11171 |
Catalog # | MBS9407550 |
Price | $200, $255 |
Order / More Info | EPB41 (Phospho-Tyr660/418) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |