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Antigenic Specificity | SWAP70 |
Clone | [434CT16.5.5] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged SWAP70 protein(Fragment) was used to produced this monoclonal antibody. Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
Immunogen | n/a |
Other Names | [Switch-associated protein 70; SWAP-70; SWAP70; KIAA0640] |
Gene, Accession # | [SWAP70], Gene ID: 23075, NCBI: NP_055870.2, UniProt: Q9UH65 |
Catalog # | MBS9200199 |
Price | $165, $370 |
Order / More Info | SWAP70 Antibody from MYBIOSOURCE INC. |
Product Specific References | Liu, J., et al. J. Histochem. Cytochem. 55(7):701-708(2007) Ihara, S., et al. J. Cell. Sci. 119 (PT 3), 500-507 (2006) : Kimbara, N., et al. Microbiol. Immunol. 50(3):235-242(2006) Hilpela, P., et al. Mol. Biol. Cell 14(8):3242-3253(2003) Rapalus, L., et al. Clin. Immunol. 101(3):270-275(2001) |