Mouse CD51 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD51 |
| Clone | [RMV-7] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.25 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse CD51 antibody, clone RMV-7 recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 |
| Immunogen | Immunogen: Cultured LAK cells from Balb/c mice. Fusion Partners: Spleen cells from immunised SD rats were fused with the cells of the P3X.63Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [integrin alpha-V; Integrin alpha-V; integrin alpha-V; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor subunit alpha; integrin alpha V; Vitronectin receptor subunit alpha; CD_antigen: CD51Cleaved into the following 2 chains:Integrin alpha-V heavy chain; Integrin alpha-V light chain], [Itgav; Itgav; CD51; 1110004F14Rik; 2610028E01Rik; D430040G12Rik] |
| Gene, Accession # | [CD51], Gene ID: 16410, NCBI: NP_032428.2, UniProt: P43406 |
| Catalog # | MBS214310 |
| Price | $430 |
| Order / More Info | Mouse CD51 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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