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Antigenic Specificity | Human HEPARANASE-1 |
Clone | [HP3/17] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b |
Format | purified |
Size | 0.1 mg |
Concentration | IgG concentration 4.0 mg/ml |
Applications | Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human Heparanase-1 antibody, clone HP3/17 is specific to Heparanase-1, also know as HPA1, an endo-beta-D-glucuronidase that degrades heparan sulfate proteoglycans (HSPGs) in the extracellular matrix through cleavage of the heparan sulfate side chains. Heparanase-1 is a heterodimer that is produced as a 65kDa latent precursor, consisting of an 8kDa subunit, a 50kDa subunit and a linker peptide. Activation of Heparanase-1 occurs through cleavage of the linker peptide, releasing the 8kDa subunit from the active 50kDa subunit. |
Immunogen | Immunogen: Polypeptide from the 50 kDa subunit of heparanase Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [heparanase isoform 1 preproprotein; Heparanase; heparanase; endo-glucoronidase; heparanase-1; heparanase; Endo-glucoronidase; Heparanase-1; Hpa1], [HPSE; HPSE; HPA; HPA1; HPR1; HSE1; HPSE1; HEP; HPA; HPA1; HPR1; HPSE1; HSE1; Hpa1] |
Gene, Accession # | Gene ID: 10855, NCBI: NP_001092010.1, UniProt: Q9Y251 |
Catalog # | MBS213416 |
Price | $935 |
Order / More Info | Human HEPARANASE-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |