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Antigenic Specificity | Sex Hormone Binding Globulin (SHBG) |
Clone | [SPM605] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis. |
Immunogen | Immunogen: Recombinant full-length human SHBG protein |
Other Names | [Androgen binding protein (ABP); Sex hormone-binding globulin (SHBG); Sex steroid binding protein (SBP); Sex steroid-binding protein; Testis-specific androgen-binding protein; Testosterone binding beta globulin; Testosterone-Estradiol-Binding Globulin (TEBG)], [SHBG; SHBG; ABP; SBP; TEBG; SHBG; SBP; ABP; TeBG] |
Gene, Accession # | [SHBG], Gene ID: 6462, NCBI: NP_001031.2, UniProt: P04278 |
Catalog # | MBS439054 |
Price | $190, $340, $340 |
Order / More Info | Sex Hormone Binding Globulin (SHBG) Antibody from MYBIOSOURCE INC. |
Product Specific References | Grishkovskaya, I., et al. 2000. Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain. EMBO. J. 19: 504-512. |