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Antigenic Specificity | GPR120 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GPR120 antibody detects endogenous levels of total GPR120. Description: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids).Function: Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizi |
Immunogen | Immunogen: A synthesized peptide derived from human GPR120 Subcellular Location: Cell Membrane. Colocalized with ARRB2 following DHA treatment. Tissue Specificity: Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (90%), Horse (90%), Sheep (90%), Rabbit (90%), Dog (91%) |
Other Names | [G protein coupled receptor 120; G protein coupled receptor 129; G protein coupled receptor GT01; G protein coupled receptor PGR 4; G protein coupled receptor PGR4; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; GPR 120; GPR 129; GPR120; GPR129; GT01; HGNC:19345; MGC119984; O3FA1_HUMAN; O3FAR1; Omega-3 fatty acid receptor 1; PGR 4; PGR4] |
Gene, Accession # | [GPR120], Gene ID: 338557, NCBI: NP_001182684.1, UniProt: Q5NUL3 |
Catalog # | MBS9601392 |
Price | $240, $280 |
Order / More Info | GPR120 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |