NFE2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNFE2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: NFE2 antibody detects endogenous levels of total NFE2. Description: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.Subunit Structure: Homodimer; can bind DNA as a homodimer. Erythroid transcription activator nuclear factor erythroid-derived 2 (N
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Nucleus > PML Body. Cytoplasm. The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH. Tissue Specificity: Expressed in hematopoietic cells and also in colon and testis. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (88%), Bovine (88%), Horse (88%), Sheep (88%), Rabbit (81%), Dog (94%)
Other Names[erythroid-derived 2 45 kDa subunit; Leucine zipper protein NF-E2; Leucine zipper protein NFE2; NF E2; nfe2; NFE2_HUMAN; Nuclear factor (erythroid derived 2), 45kDa; nuclear factor (erythroid-derived 2), 45kD; Nuclear factor; nuclear factor, erythroid 2; Nuclear factor, erythroid derived 2 45 kDa subunit; p45; p45 NF-E2; p45 NFE2; Transcription factor NF-E2 45 kDa subunit; Transcription factor NFE2 45 kDa subunit]
Gene, Accession #[NFE2], Gene ID: 4778, NCBI: NP_001129495.1, UniProt: Q16621
Catalog #MBS9604109
Price$240, $280
Order / More InfoNFE2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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