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Antigenic Specificity | MRGPRX2 (MRGX2, Mas-related G-protein Coupled Receptor Member X2) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 0.36mg/ml |
Applications | Western Blot (WB), Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human MRGPRX2. MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. |
Immunogen | Immunogen: Full length human MRGPRX2, aa1-330 (NP 473371.1). |
Other Names | [-MRGPRX2 (MRGX2, Mas-related G-protein Coupled Receptor Member X2)] |
Gene, Accession # | Gene ID: 117194, NCBI: NP_473371.1, UniProt: Q96LB1 |
Catalog # | MBS6010259 |
Price | $580 |
Order / More Info | MRGPRX2 (MRGX2, Mas-related G-protein Coupled Receptor Member X2) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |