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Antigenic Specificity | Human CD19 |
Clone | [4ACB19] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4ACB19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.* CD19 is a key phenotyping marker of non-T cell leukemia. |
Immunogen | n/a |
Other Names | [CD19, partial; B-lymphocyte antigen CD19; B-lymphocyte antigen CD19; CD19 molecule; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD_antigen: CD19] |
Gene, Accession # | [CD19], Gene ID: 930, NCBI: AAD02340.1 |
Catalog # | MBS8500826 |
Price | $280, $300 |
Order / More Info | Human CD19 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Nadler, LM et al. (1983) J. Immunol. 131:244. 2. Schlossman, SL et al., eds. (1995) Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York. 3. Tedder T. et al. (1994) Immunol Today. 15:437-442. |