ZFYVE28 (Zinc Finger FYVE-type containing 28) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ZFYVE28 (Zinc Finger FYVE-type containing 28) |
| Clone | [LST2/2426] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE d |
| Immunogen | Immunogen: Recombinant full-length human ZFYVE28 protein |
| Other Names | [Lateral signaling target protein 2 homolog; LST2; LYST2; Zinc finger FYVE domain-containing protein 28 (ZFYVE28)] |
| Gene, Accession # | [ZFYVE28], Gene ID: 57732 |
| Catalog # | MBS4381210 |
| Price | $190, $340, $340 |
| Order / More Info | ZFYVE28 (Zinc Finger FYVE-type containing 28) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.Dev. Cell 16:687-698, 2009. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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