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Antigenic Specificity | IRAK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Interleukin-1 receptor-associated kinase 4(IRAK4) detection. Tested with WB in Human, Mouse, Rat. Background: IRAK-4(interleukin-1 receptor-associated kinase 4), also called REN64, in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It also supports signaling from T-cell receptors. Scott(2002) mapped the REN64/IRAK4 gene to chromosome 12 based on similarity between the REN64 sequence(GenBank AF155118) and a chromosome 12 clone(GenBank AC093012). Functional analysis by Li et al.(2002) determined that IRAK4, like IRAK1 and Pelle, has auto- and cross-phosphorylation kinase activity. Precipitation and binding analyses showed weak interact |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IRAK4 (45-59aa DDRYNQFHIRRFEAL), identical to the related rat and mouse sequences. |
Other Names | [Interleukin-1 receptor-associated kinase 4; interleukin-1 receptor-associated kinase 4; IL-1 receptor-associated kinase 4; Interleukin 1 receptor associated kinase 4 mutant form 1; Interleukin-1 receptor-associated kinase 4; Interleukin1 receptor associated kinase 4; IPD1; IRAK 4; IRAK-4; IRAK4; IRAK4 mutated form 1; IRAK4_HUMAN; LOC 51135; NY REN 64; NY REN 64 antigen; NY-REN-64; REN64; Renal carcinoma antigen NY-REN-64], [IRAK4; IRAK4; IPD1; REN64; IRAK-4; NY-REN-64; IRAK-4] |
Gene, Accession # | [IRAK4], Gene ID: 51135, NCBI: Q9NWZ3.1, UniProt: Q9NWZ3 |
Catalog # | MBS176135 |
Price | $280 |
Order / More Info | IRAK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |