Elastin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityElastin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Elastin antibody detects endogenous levels of total Elastin. Function: Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).Subunit Structure: The polymeric elastin chains are cross-linked together into an extensible 3D network. Forms a ternary complex with BGN and MFAP2. Interacts with MFAP2 via divalent cations (calcium > magnesium > manganese) in a dose-dependent and saturating manner. Interacts with FBLN5 (PubMed:15790312, PubMed:17035250). Interacts with FBN1 (PubMed:15790312). F
ImmunogenImmunogen: A synthesized peptide derived from human Elastin Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Extracellular matrix of elastic fibers. Tissue Specificity: Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin.
Other Names[Elastin; ELN; ELN_HUMAN; SVAS; Tropoelastin; WBS; WS]
Gene, Accession #[ELN], Gene ID: 2006, NCBI: NP_000492.2, UniProt: P15502
Catalog #MBS9601399
Price$240, $280
Order / More InfoElastin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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