KMT2A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKMT2A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.06 mL, 0.12 mL, 0.2 mL
Concentration1 mg/mL
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene a
ImmunogenImmunogen: Recombinant protein of human KMT2A
Other Names[ALL-1; ALL1; C-terminal cleavage product of 180 kDa; CXXC-type zinc finger protein 7; CXXC7; HRX; HTRX1; KMT2A; Lysine N-methyltransferase 2A; Mll; MLL cleavage product C180; MLL1; MLL1; MLL1A; N-terminal cleavage product of 320 kDa; p180; p320; Trithorax-like protein; TRX1; Zinc finger protein HRX]
Gene, Accession #[KMT2A], Gene ID: 4297, NCBI: NP_001184033.1, UniProt: Q03164
Catalog #MBS2554517
Price$150, $225, $360
Order / More InfoKMT2A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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