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Antigenic Specificity | KMT2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene a |
Immunogen | Immunogen: Recombinant protein of human KMT2A |
Other Names | [ALL-1; ALL1; C-terminal cleavage product of 180 kDa; CXXC-type zinc finger protein 7; CXXC7; HRX; HTRX1; KMT2A; Lysine N-methyltransferase 2A; Mll; MLL cleavage product C180; MLL1; MLL1; MLL1A; N-terminal cleavage product of 320 kDa; p180; p320; Trithorax-like protein; TRX1; Zinc finger protein HRX] |
Gene, Accession # | [KMT2A], Gene ID: 4297, NCBI: NP_001184033.1, UniProt: Q03164 |
Catalog # | MBS2554517 |
Price | $150, $225, $360 |
Order / More Info | KMT2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |