LIM Kinase 1 (LIMK1) (N-term), 1-30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLIM Kinase 1 (LIMK1) (N-term), 1-30
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
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DescriptionThis LIM Kinase 1 (LIMK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LIM Kinase 1 (LIMK1). LIMK1, a member of the Ser/Thr protein kinase family, may be a component of an intracellular signaling pathway and may be involved in brain development. It phosphorylates and inactivates the actin binding/depolymerizing factor cofilin and induces actin cytoskeletal changes. The LIM domain interacts with the cytoplasmic domain of NRG1, and this cytoplasmic protein also binds ROCK1, whic phosphorylates LIMK1 on serine and/or threonine residues. Highest expression occurs in both adult and fetal nervous systems. It is detected ubiquitously throughout the
Immunogenn/a
Other Names[LIM domain kinase 1; LIMK-1; LIMK1; LIMK]
Gene, Accession #[LIMK1], Gene ID: 3984, NCBI: NP_001191355.1, UniProt: P53667
Catalog #MBS9207050
Price$165, $370
Order / More InfoLIM Kinase 1 (LIMK1) (N-term), 1-30 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesOhashi, K., et al., J. Biol. Chem. 275(5):3577-3582 (2000). Maekawa, M., et al., Science 285(5429):895-898 (1999). Edwards, D.C., et al., J. Biol. Chem. 274(16):11352-11361 (1999). Osborne, L.R., et al., Genomics 36(2):328-336 (1996). Frangiskakis, J.M., et al., Cell 86(1):59-69 (1996).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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