NUP214 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNUP214
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: NUP214 antibody detects endogenous levels of total NUP214. Function: May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex.Subunit Structure: Homodimer. Interacts with ZFP36; this interaction increases upon lipopolysaccharide (LPS) stimulation (PubMed:14766228). Interacts with DDX19 (PubMed:19219046, PubMed:19208808). Interacts with NUP88 (PubMed:9049309). Interacts with XPO1 (PubMed:9049309). Interacts with XPO5 (PubMed:11777942).Post-translational Modifications: Probably glycosylated as it reacts with wheat germ agglutinin (WGA).Similarity: Contains FG repeats.The beta-propeller contains long interblade connector loops, and mediates interaction with DDX19B.
ImmunogenImmunogen: A synthesized peptide derived from human NUP214 Subcellular Location: Nucleus > Nuclear Pore Complex. Cytoplasmic Filaments. Tissue Specificity: Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development.
Other Names[214 kDa nucleoporin; CAIN; CAN; CAN protein putative oncogene; D9S46E; N214; NU214_HUMAN; Nuclear pore complex protein Nup214; nucleoporin 214kDa; Nucleoporin Nup214; Nup214; p250; Protein CAN]
Gene, Accession #[NUP214], Gene ID: 8021, NCBI: NP_001305253.1, UniProt: P35658
Catalog #MBS9610027
Price$240, $280
Order / More InfoNUP214 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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