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Antigenic Specificity | NUP214 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NUP214 antibody detects endogenous levels of total NUP214. Function: May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex.Subunit Structure: Homodimer. Interacts with ZFP36; this interaction increases upon lipopolysaccharide (LPS) stimulation (PubMed:14766228). Interacts with DDX19 (PubMed:19219046, PubMed:19208808). Interacts with NUP88 (PubMed:9049309). Interacts with XPO1 (PubMed:9049309). Interacts with XPO5 (PubMed:11777942).Post-translational Modifications: Probably glycosylated as it reacts with wheat germ agglutinin (WGA).Similarity: Contains FG repeats.The beta-propeller contains long interblade connector loops, and mediates interaction with DDX19B. |
Immunogen | Immunogen: A synthesized peptide derived from human NUP214 Subcellular Location: Nucleus > Nuclear Pore Complex. Cytoplasmic Filaments. Tissue Specificity: Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development. |
Other Names | [214 kDa nucleoporin; CAIN; CAN; CAN protein putative oncogene; D9S46E; N214; NU214_HUMAN; Nuclear pore complex protein Nup214; nucleoporin 214kDa; Nucleoporin Nup214; Nup214; p250; Protein CAN] |
Gene, Accession # | [NUP214], Gene ID: 8021, NCBI: NP_001305253.1, UniProt: P35658 |
Catalog # | MBS9610027 |
Price | $240, $280 |
Order / More Info | NUP214 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |