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Antigenic Specificity | Human CD283 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human CD283 antibody recognizes human CD283, otherwise known as toll receptor 3, a 103.8kDa member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the placenta and pancreas and also expressed by dendritic cells. TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, and has been shown to recognize double-stranded viral RNA, including that of the Influenza A and West Nile virus. Rabbit anti Human CD283 antibody has been shown as suitable for use in IHC on EL4 cytospins at 1ug/ |
Immunogen | Immunogen: Synthetic peptide corresponding to a 15 amino acid sequence located near human CD283 carboxy-terminus. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human CD283 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by ion exchange chromatography. Target Species: Human |
Other Names | [toll-like receptor 3; Toll-like receptor 3; toll-like receptor 3; toll-like receptor 3; CD_antigen: CD283], [TLR3; TLR3; CD283; IIAE2] |
Gene, Accession # | [CD283], Gene ID: 7098, NCBI: NP_003256.1, UniProt: O15455 |
Catalog # | MBS221327 |
Price | $375 |
Order / More Info | Human CD283 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |