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Antigenic Specificity | CD34 |
Clone | [ICO-115] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD34 a type 1 transmembrane protein, belonging to the sialomucin family, has important roles in adhesion which remain to be fully elucidated. CD34 has an intracellular cytoplasmic domain containing consensus sites for serine, theronine, tryrosine and active protein kinase C (PKC) phosphorylation thereby implicating a role for the protein in signal transduction processes. CD34 expression, as identified by antibody, is a hallmark for identifying pluripotential hematopoietic stem or progenitor cells. CD34 antibody positive populations expand and differentiate into the various lymphohematopoietic lineages. During differentiation, lineages lose CD34 expression and become CD34 antibody negative. |
Immunogen | Antigen: CD34. Immunogen Information: Blast cells from a chronic myeloid leukemia patient were used as the immunogen for the CD34 antibody. Conjugation: Unconjugated |
Other Names | [CD34], [CD34; CD34] |
Gene, Accession # | [CD34], Gene ID: 947, NCBI: NP_001020280.1, UniProt: P28906 |
Catalog # | MBS669134 |
Price | $115, $160 |
Order / More Info | CD34 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |