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Antigenic Specificity | CD86 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.50-0.75 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified T-lymphocyte activation antigen CD86 isoform 1 precursor Antibody. Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 250-329 on human CD86 protein. Expression: Expressed by activated B-lymphocytes and monocytes. |
Other Names | [Activation B7 2 antigen; B-lymphocyte activation antigen B7-2; B7 2; B70; BU63; CD 86; CD28 antigen ligand 2 2; CLS1; CTLA 4 counter receptor B7 2; Early T-cell costimulatory molecule 1; ETC-1; FUN 1; LAB72; Ly-58; MB7-2; Membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2], [CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2] |
Gene, Accession # | [CD86], Gene ID: 942, NCBI: NP_787058, UniProt: P42081 |
Catalog # | MBS540331 |
Price | $390 |
Order / More Info | CD86 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |