PARL Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PARL antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PARL |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins. PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1, a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals. In lymphocytes and neurons, PARL's association with other proteins, such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL, preventing the accumulation of Bax, thereby suppressing apoptosis. Variations in this gene have been associated with increased risk for type 2 diabetes. PARL may also play a role in the progression of Alzheimer's disease |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide from near the amino terminus of human PARL. |
| Other Names | [Presenilin-associated rhomboid-like protein, PSARL, PSARL1, PSNENIP2] |
| Gene, Accession # | [PARL], Gene ID: 55486, NCBI: NP_001032728.1, UniProt: Q9H300 |
| Catalog # | MBS9413253 |
| Price | $320 |
| Order / More Info | PARL Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies