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Antigenic Specificity | IL-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect IL-10 in human, mouse and rat samples. Background: IL-10 (Interleukin-10), originally known as Cytokine Synthesis Inhibitory Factor (CSIF), is an 20.5 kDa protein containing 161-178 amino acid residues. IL10 is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytok |
Immunogen | Immunogen: Recombinant human protein. Positive Control: Western Blot: Jurkat cell lysate |
Other Names | [CSIF; IL-10; IL10A; TGIF; B-TCGF; GVHDS; MGC126450; MGC126451; RP11-262N9.1; Interleukin-10], [IL10; IL10; CSIF; TGIF; GVHDS; IL-10; IL10A; IL-10; CSIF] |
Gene, Accession # | [IL-10], Gene ID: 3586, NCBI: NP_000563.1, UniProt: P22301 |
Catalog # | MBS840916 |
Price | $150, $325 |
Order / More Info | IL-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |