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Antigenic Specificity | GSK-3a |
Clone | [SBGSK3 alpha 1] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | peroxidase (HRP) conjugate |
Size | 1 mL |
Concentration | n/a |
Applications | Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, mouse and rat GSK-3 alpha. Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. |
Immunogen | n/a |
Other Names | [Mouse GSK-3a - HRP; Mouse GSK-3 alpha], [GSK3A; GSK3A; DKFZp686D0638] |
Gene, Accession # | Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS670116 |
Price | $435 |
Order / More Info | GSK-3a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |