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Antigenic Specificity | TACE (CT), ADAM 17 (CT), (TNFa Converting Enz) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tumor-necrosis factor- is a proinflammatory cytokine and contributes to a variety of inflammatory disease responses and programmed cell death. TNF- is synthesized as a 26K type II membrane-bound precursor that is cleaved by a convertase to generate secreted 17K mature TNF-. TNF- converting enzyme (TACE) protein was recently purified and the human and mouse TACE cDNAs were cloned by several groups separately (1-3). TACE is a membrane-bound metalloprotease-disintegrin in the family of mammalian ADAM (for a disintegrin and metalloprotease). TACE also processes other cell surface proteins, including TNF receptor, TGF, the L-selectin adhesion molecule, and alpha-cleavage of amyloid protein precursor (APP) (4,5). TACE mRNA is expressed in a varie |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 807 to 823 of the human TACE protein. Immunogen sequence differs from the mouse and rat sequences by one amino acid. |
Other Names | [TNF- Converting Enzyme C-terminal; ADAM17; CSVP; TACE], [ADAM17; ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B; CSVP; TACE; ADAM 17] |
Gene, Accession # | [TACE], Gene ID: 6868, NCBI: NP_003174.3, UniProt: P78536 |
Catalog # | MBS395641 |
Price | $510 |
Order / More Info | TACE (CT), ADAM 17 (CT), (TNFa Converting Enz) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |