LFA3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-LFA3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | LFA3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human. |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Lymphocyte function-associated antigen 3 (CD58) detection. Background: CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. The LFA3 gene is mapped to chromosome 1p13, which is the same locati |
| Immunogen | Immunogen: E Coli-derived human LFA3 recombinant protein (Position: F29-R215). |
| Other Names | [AG3; CD58; CD58 antigen; CD58 molecule; LFA 3; LFA-3; LFA3; P19256; Lymphocyte function-associated antigen 3; CD58 molecule], [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3] |
| Gene, Accession # | [CD58], Gene ID: 965, NCBI: NP_001138294.1, UniProt: P19256 |
| Catalog # | MBS178408 |
| Price | $315 |
| Order / More Info | LFA3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Barbosa, J. A., Mentzer, S. J., Kamarck, M. E., Hart, J., Biro, P. A., Strominger, J. L., Burakoff, S. J. Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions. J. Immun. 136: 3085-3091, 1986. 2. Sewell, W. A., Palmer, R. W., Spurr, N. K., Sheer, D., Brown, M. H., Bell, Y., Crumpton, M. J. The human LFA-3 gene is located at the same chromosome band as the gene for its receptor CD2. Immunogenetics 28: 278-282, 1988. 3. Wang, J., Smolyar, A., Tan, K., Liu, J., Kim, M., Sun, Z. J., Wagner, G., Reinherz, E. L. Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97: 791-803, 1999. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies