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Antigenic Specificity | Mouse CD81 |
Clone | [2F7] |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG, group 3, kappa |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mouse CD81 (Mr 25 kDa), a member of the transmembrane 4 integral membrane protein family. CD81/TAPA-1 is an integral membrane protein expressed on a variety of cell types, and has a high degree of sequence homology between human and mouse.1 CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma delta + T cells to more mature T cells with alpha beta T cell receptors.2 Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor, which is composed of a TCR beta chain and glycoprotein pT alp |
Immunogen | Immunogen: Mouse epithelial cell line PAM212 |
Other Names | [Hamster Mouse CD81 - Purified, Unlabeled; Hamster Mouse CD81/TAPA-1], [CD81; CD81; S5.7; CVID6; TAPA1; TSPAN28; TAPA1; TSPAN28] |
Gene, Accession # | Gene ID: 975, NCBI: NP_004347.1, UniProt: P60033 |
Catalog # | MBS673604 |
Price | $280 |
Order / More Info | Mouse CD81 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Andria, M.L., et al. 1991. J. Immunol. 147:1030.2. Boismenu, R., M. Rhein, W.H. Fischer, and W.L. Harven. 1996. Science 271:198. |