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Antigenic Specificity | Histone Methyltransferase (SUV39H1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, Drosophila |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: The histone methyltransferase KMT1A / SUV39H1 is the mammalian homologue of the Drosophila PEV modifier Su(var)3-9 protein. SUV39H1 contains the SET and chromo domains. In eukaryotic cells, SUV39H1 and the methyl-lysine binding protein HP1 interact to repress transcription at heterochromatic sites. SUV39H1 methylates histone H3 on lysine 9, which generates a binding site for HP1 proteins that plays a role in heterochromatin formation and gene silencing. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 389 of mouse Histone Methyltransferase. Positive Control: 3T3 cell lysate |
Other Names | [Histone-lysine N-methyltransferase; SUV39H1; Histone H3-K9 methyltransferase 1; H3-K9-HMTase 1; Full=Position-effect variegation 3-9 homolog; Suppressor of variegation 3-9 homolog 1; Su(var)3-9 homolog 1], [Suv39h1; Suv39h1; mIS6; KMT1A; AI852103; AL022883; DXHXS7466e; H3-K9-HMTase 1; Suv39h; H3-K9-HMTase 1; Su(var)3-9 homolog 1] |
Gene, Accession # | Gene ID: 20937, NCBI: NP_035644.1 |
Catalog # | MBS841013 |
Price | $150, $290 |
Order / More Info | Histone Methyltransferase (SUV39H1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |