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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Peptide affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase 3 antibody detects endogenous levels of Caspase 3 protein. Not tested with other proteins. This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta4A precursor protein, which is associated with neuronal death |
Immunogen | Immunogen: peptide from the intermediate residues of human Caspase 3 protein |
Other Names | [Homo sapiens caspase 3, apoptosis-related cysteine peptidase (CASP3), transcript variant alpha, mRNA; Caspase-3; caspase-3; CASP-3; CPP-32; PARP cleavage protease; SREBP cleavage activity 1; apopain; caspase 3, apoptosis-related cysteine protease; cysteine protease CPP32; procaspase3; protein Yama; caspase 3, apoptosis-related cysteine peptidase; Apopain; Cysteine protease CPP32; CPP-32], [CASP3; CASP3; CPP32; SCA-1; CPP32B] |
Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2 |
Catalog # | MBS416637 |
Price | $230 |
Order / More Info | Caspase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Cerulo,, G. et al. Serotonin activates cell survival and apoptotic death responses in cultured epithelial thyroid cells. Biochimie 105:211-216 (2014). PubMed: 24997405.Cerulo, G et al. Serotonin activates cell survival and apoptotic death responses in cultured epithelial thyroid cells. Biochimie 105:211-215 (2014). PubMed: 24997405. |