Tetanus Toxin, Clostridium tetani (Tetanospasmin, TeNT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTetanus Toxin, Clostridium tetani (Tetanospasmin, TeNT)
Clone[9B138]
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
FormatProtein G purified
Size1 mg
Concentration10.7 mg/ml
ApplicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionRecognizes the tetanus toxin. Has toxin neutralization activity (in vivo assay). Tetanus toxin is polypeptide composed of two chains [A chain (55kD) and B chain (105kD)]. The toxin is carried to CNS via bloodstream. Tetanus toxin binds at neuromuscular synapses via ganglioside receptors (sialic acid) via B-chain. The toxin is then internalized via receptor-mediated endocytosis. The A chain is thought to be the toxic subunit by analogy to diptheria and cholera toxin. It has no known effect on any cellular enzyme systems. The action of the holotoxin (A + B chains) is to interfere with synaptic transmission by preferentially inhibiting the release of inhibitory neurotransmitters such as glycine and GABA from inhibitory neurons. This inhibition
ImmunogenImmunogen: Supernatant from C. tetani.
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS632310
Price$730
Order / More InfoTetanus Toxin, Clostridium tetani (Tetanospasmin, TeNT) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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