ARHGEF7 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ARHGEF7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total ARHGEF7 protein. Cool/Pix proteins comprise a family of guanine nucleotide exchange factors (GEFs) localized to focal adhesions. The family consists of two isoforms, cool2/apix and cool1/bPix, the latter having two splice variants that vary in their carboxy termini (1). Cool1/bPix, like other GEFs, has a DH (Dbl homology) domain, which allows binding of small GTPases and GDP/GTP exchange, and a PH (Pleckstrin homology) domain, which is important in regulating subcellular localization. Cool1/bPix also has an SH3 domain, which binds to the PAK kinase, a downstream effector of cdc42 and Rac (3,4). Phosphorylation of cool1/bPix by PAK2 downstream of MAPK signaling alters the localization of a compl |
| Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human ARHGEF7. |
| Other Names | [ARHGEF7; BETA-PIX; COOL1; DKFZp686C12170; DKFZp761K1021] |
| Gene, Accession # | [ARHGEF7], Gene ID: 8874, NCBI: NP_001106983.1, UniProt: Q14155 |
| Catalog # | MBS9408567 |
| Price | $255 |
| Order / More Info | ARHGEF7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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