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Antigenic Specificity | Human TAR DNA-binding protein 43 |
Clone | [Pk1B8AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome which produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. TARDBP is a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. |
Immunogen | Immunogen: Anti-human TARDBP mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TARDBP amino acids 1-260 purified from E Coli. |
Other Names | [TARDBP; TAR DNA-binding protein 43, Mouse Human; TAR DNA-binding protein 43; TDP-43; TARDBP; TDP43; ALS10], [TARDBP; TARDBP; ALS10; TDP-43; TDP43; TDP-43] |
Gene, Accession # | [TARDBP], Gene ID: 23435, NCBI: NP_031401.1 |
Catalog # | MBS140318 |
Price | $140, $205, $505 |
Order / More Info | Human TAR DNA-binding protein 43 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |