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Antigenic Specificity | GRM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple tra |
Immunogen | Immunogen: Recombinant protein of human GRM1 (NP 000829.2). |
Other Names | [Metabotropic glutamate receptor 1; Metabotropic glutamate receptor 1; metabotropic glutamate receptor 1; glutamate metabotropic receptor 1] |
Gene, Accession # | [GRM1], Gene ID: 2911, NCBI: Q13255.3, UniProt: Q13255 |
Catalog # | MBS8566870 |
Price | $280 |
Order / More Info | GRM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |