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Antigenic Specificity | FGFR1 (Phospho-Tyr766) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of FGFR1 only when phosphorylated at tyrosine 766. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 766 (Q-E-Y(p)-L-D) derived from FGFR1. |
Other Names | [FGFBR; FGFR-1; FLG; FLT2; c-fgr] |
Gene, Accession # | [FGFR1], Gene ID: 2260, NCBI: NP_001167534.1, UniProt: P11362 |
Catalog # | MBS9404699 |
Price | $200, $255 |
Order / More Info | FGFR1 (Phospho-Tyr766) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |