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Antigenic Specificity | CBX8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CBX8 antibody detects endogenous levels of total CBX8. Function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.Subunit Structure: Component of a PRC1-like complex. Interacts with RING1 RNF2, PCGF1, PCGF2, PCGF3, BMI1, PCGF5 AND PCGF6. Interacts with MLLT3 and histone H3. Interacts with PHC2 (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human CBX8 Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit Similarity: Pig (89%), Bovine (89%), Sheep (89%), Rabbit (100%) |
Other Names | [Cbx8; CBX8_HUMAN; Chromobox Homolog 8 (Drosophila Pc Class); Chromobox Homolog 8 (Pc Class Homolog, Drosophila); Chromobox Homolog 8; Chromobox protein homolog 8; hPc3; Pc Class 3 Homolog (Drosophila); Pc Class 3 Homolog; Pc3; Polycomb 3; Polycomb 3 homolog; RC1; Rectachrome 1] |
Gene, Accession # | [CBX8], Gene ID: 57332, NCBI: NP_065700.1, UniProt: Q9HC52 |
Catalog # | MBS9609189 |
Price | $240, $280 |
Order / More Info | CBX8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |