AUP1 (C-term), 440-468 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAUP1 (C-term), 440-468
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis AUP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the C-terminal region of human AUP1. This gene encodes a protein that contains a domain withhomology to the ancient conserved region of the archain 1 gene anda domain that may be involved in binding ubiquitin-conjugatingenzymes. The protein encoded by this gene has been shown to bind tothe conserved membrane-proximal sequence of the cytoplasmic tail ofintegrin alpha(IIb) subunits. These subunits play a crucial role inthe integrin alpha(IIb)beta(3) inside-out signalling in plateletsand megakaryocytes that leads to platelet aggregation and thrombusformation. This gene overlaps the gene
Immunogenn/a
Other Names[Ancient ubiquitous protein 1; AUP1]
Gene, Accession #[AUP1], Gene ID: 550, NCBI: NP_853553.1, UniProt: Q9Y679
Catalog #MBS9209194
Price$165, $370
Order / More InfoAUP1 (C-term), 440-468 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesEwing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Kato, A., et al. J. Biol. Chem. 277(32):28934-28941(2002) Karpisheva, K.V., et al. Tsitologiia 44(9):846-851(2002) Karpisheva, K.V., et al. Tsitologiia 44(9):839-845(2002) Jang, W., et al. Genomics 36(2):366-368(1996)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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