Edit |   |
---|---|
Antigenic Specificity | CCS/SOD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CCS antibody detects endogenous levels of total CCS. Function: Delivers copper to copper zinc superoxide dismutase (SOD1).Subunit Structure: Homodimer, and heterodimer with SOD1. Interacts with COMMD1. Interacts with XIAP/BIRC4.Post-translational Modifications: Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241.Similarity: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Horse, Sheep, Rabbit Similarity: Pig (80%), Horse (90%), Sheep (80%), Rabbit (90%) |
Other Names | [CCS; CCS_HUMAN; Copper chaperone for superoxide dismutase; MGC138260; SOD 4; SOD4; Superoxide dismutase copper chaperone] |
Gene, Accession # | [CCS], Gene ID: 9973, NCBI: NP_005116.1, UniProt: O14618 |
Catalog # | MBS9605427 |
Price | $240, $280 |
Order / More Info | CCS/SOD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |