Oct-4 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Oct-4 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is produced by immunizing mouse with Oct-4 recombinant protein. Oct-4 (POU5F1) is transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Oct-4 is critical for early embryogenesis and for embryonic stem cell pluripotency. It is expressed in developing brain and highest levels also found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. |
| Immunogen | n/a |
| Other Names | [POU domain, class 5, transcription factor 1 isoform 3; POU domain, class 5, transcription factor 1; POU domain, class 5, transcription factor 1; POU class 5 homeobox 1; Octamer-binding protein 3; Oct-3; Octamer-binding protein 4; Oct-4; Octamer-binding transcription factor 3; OTF-3], [POU5F1; POU5F1; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; OCT3; OCT4; OTF3; Oct-3; Oct-4; OTF-3] |
| Gene, Accession # | [OCT-4], Gene ID: 5460, NCBI: NP_001272916.1, UniProt: Q01860 |
| Catalog # | MBS857226 |
| Price | $280 |
| Order / More Info | Oct-4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Oct4 pseudogenes are transcribed in cancers.Suo G., Han J., Wang X., Zhang J., Zhao Y., Zhao Y., Dai J.Biochem. Biophys. Res. Commun. 337:1047-1051(2005). Sumoylation of Oct4 enhances its stability, DNA binding, and transactivation.Wei F., Schoeler H.R., Atchison M.L.J. Biol. Chem. 282:21551-21560(2007). Post-translational modification of POU domain transcription factor Oct-4 by SUMO-1.Zhang Z., Liao B., Xu M., Jin Y.FASEB J. 21:3042-3051(2007). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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