Edit |   |
---|---|
Antigenic Specificity | LTB (C-term), 199-227 |
Clone | [399CT9.3.4] |
Host Species | Mouse |
Reactive Species | human (predicted reactivity: porcine) |
Isotype | IgM |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LTB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB. Lymphotoxin beta is a type II membrane protein of the TNFfamily. It anchors lymphotoxin-alpha to the cell surface throughheterotrimer formation. The predominant form on the lymphocytesurface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 moleculealpha/2 molecules beta) and this complex is the primary ligand forthe lymphotoxin-beta receptor. The minor complex islymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatoryresponse system and involved in normal development of lymphoidtissue. Lymphotoxin-beta isoform b is unable to complex withl |
Immunogen | n/a |
Other Names | [Lymphotoxin-beta; LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3; LTB; TNFC; TNFSF3] |
Gene, Accession # | [LTB], Gene ID: 4050, NCBI: NP_002332.1, UniProt: Q06643 |
Catalog # | MBS9200068 |
Price | $370 |
Order / More Info | LTB (C-term), 199-227 Antibody from MYBIOSOURCE INC. |
Product Specific References | Clancy, R.M., et al. Arthritis Rheum. 62(11):3415-3424(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Young, J., et al. Cytokine 51(1):78-86(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) |