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Antigenic Specificity | Human CD206 |
Clone | [7-450] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.2 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Frozen |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD206 antibody, clone 7-450 recognizes human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and |
Immunogen | Immunogen: Monocyte-derived dendritic cells. Histology Positive Control Tissue: Human tonsil. Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the X63-Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [macrophage mannose receptor 1; Macrophage mannose receptor 1; macrophage mannose receptor 1; C-type lectin domain family 13 member D; macrophage mannose receptor 1-like protein 1; mannose receptor, C type 1-like 1; mannose receptor, C type 1; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD_antigen: CD206], [MRC1; MRC1; MMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; CLEC13D; CLEC13DL; MRC1L1; MMR] |
Gene, Accession # | [CD206], Gene ID: 4360, NCBI: NP_002429.1, UniProt: P22897 |
Catalog # | MBS214361 |
Price | $430 |
Order / More Info | Human CD206 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |