Phospho-CUL4B (Thr48) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-CUL4B (Thr48)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshumanpredicted: porcine, bovine, sheep, rabbit, dog
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-CUL4B(Thr48) Antibody detects endogenous levels of CUL4B only when phosphorylated at Thr48. Description: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Plays a role as part of the E3 ubiquitin-protein ligase complex in polyubiquitination of CDT1, histone H2A, histone H3 and histone H4 in response to radiation-induced
ImmunogenImmunogen: A synthesized peptide derived from human CUL4B around the phosphorylation site of Thr48.
Other Names[CUL 4B; CUL-4B; CUL4B; CUL4B_HUMAN; Cullin-4B; DKFZp686F1470; KIAA0695; MRXHF2; MRXSC; SFM2]
Gene, Accession #[CUL4B], Gene ID: 8450, NCBI: Q13620.4, UniProt: Q13620
Catalog #MBS9610445
Price$225, $280, $340
Order / More InfoPhospho-CUL4B (Thr48) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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