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Antigenic Specificity | SLC6A4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human SLC6A4. Species Crossreactivity: mouse. This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. |
Immunogen | Immunogen: SLC6A4 (AAH69484.1, 1-630aa) full-length human protein. |
Other Names | SLC6A4 (Solute Carrier Family 6 Member 4, Sodium-dependent Serotonin Transporter, 5HT Transporter, 5HTT, HTT, SERT) |
Gene, Accession # | Gene ID: 6532, NCBI: NP_001036.1, UniProt: P31645 |
Catalog # | MBS628823 |
Price | $615 |
Order / More Info | SLC6A4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |