Mouse Cdkn2a (Center), 39-65 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Mouse Cdkn2a (Center), 39-65 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Mouse Cdkn2a (Center), 39-65 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Cdkn2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the Central region of mouse Cdkn2a. Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional a |
| Immunogen | n/a |
| Other Names | [Cyclin-dependent kinase inhibitor 2A; isoform 3; p19ARF; Cdkn2a {ECO:0000312|EMBL:AAB357701; ECO:0000312|MGI:MGI:104738}] |
| Gene, Accession # | [Cdkn2a], Gene ID: 12578, NCBI: NP_034007.1, UniProt: Q64364 |
| Catalog # | MBS9204567 |
| Price | $165, $370 |
| Order / More Info | Mouse Cdkn2a (Center), 39-65 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nogueira, C., et al. Oncogene 29(47):6222-6232(2010) Fernandez-Diaz, L.C., et al. Development 137(20):3393-3403(2010) Bennecke, M., et al. Cancer Cell 18(2):135-146(2010) Negishi, M., et al. PLoS ONE 5 (8), E12373 (2010) : Ulanet, D.B., et al. PLoS ONE 5 (8), E12454 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies