RIP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRIP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatserum
Size0.05 mL
Concentrationn/a
ApplicationsImmunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
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DescriptionRIP (Receptor Interacting Protein) is a 74 kD Ser/Thr kinase which interacts with CD95 (Fas/APO1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRADD, RAID (CRADD) and TRAF2. RIP contains an N terminal region with homology to protein kinases, an intermediate domain capable of association with MAPKKK and a C terminal region containing an intracellular death domain motif. RIP activates both p38 MAP Kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF-kB activation. NF-kB activation through TRADD, TRAF2 and RIP can be triggered also by DR3/APO3 upon activation with APO3/Tweak ligand. DR4 and DR5 also use FADD, TRADD, and
ImmunogenImmunogen Information: A synthetic peptide of human RIP1 (amino acids 269-287 EANPEARPTFPGIEEKFRP) was used as immunogen for this antibody
Other Names[AGFG1; HRB; RAB; RIP; HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein; to RIP1/TANK; RIP1/TANK; RIP1/TANK], [AGFG1; AGFG1; HRB; RAB; RIP; HRB; RAB; RIP]
Gene, Accession #[RIP], Gene ID: 3267, NCBI: P52594.2, UniProt: P52594
Catalog #MBS668767
Price$270
Order / More InfoRIP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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