CD43/SPN Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD43/SPN |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2b |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for CD43/SPN detection. Tested with WB, IHC-P in Human; Mouse; Rat.Background: CD43, also known as leukosialin or sialophorin, is a transmembrane cell surface protein that in humans is encoded by the SPN gene. It is mapped to 16p11.2. It is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome, suggesting that CD43 have a role in |
| Immunogen | Immunogen: E Coli-derived human CD43 recombinant protein (Position: A272-P400). Human CD43 shares 72% and 73% amino acid (aa) sequence identity with mouse and rat CD43, respectively. Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P). |
| Other Names | [Leukosialin; sialophorin; Leukosialin; GPL115; Galactoglycoprotein; GALGP; Leukocyte sialoglycoprotein; Sialophorin; CD43; CD43 cytoplasmic tail; CD43-ct; CD43ct; SPN; CD43] |
| Gene, Accession # | [CD43/SPN], Gene ID: 6693, NCBI: NP_001025459.1, UniProt: P16150 |
| Catalog # | MBS1752805 |
| Price | $315 |
| Order / More Info | CD43/SPN Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Fukuda M, Carlsson SR (1987). Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens.. Med. Biol. 64 (6): 335-43. 2. Rogaev EI, Keryanov SA (1993). Unusual variability of the complex dinucleotide repeat block at the SPN locus.. Hum. Mol. Genet. 1 (8): 657. 3. Rosenstein Y, Park JK, Hahn WC, et al. (1992). CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1.. Nature 354 (6350): 233-5. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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