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Antigenic Specificity | CD3G |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD3G antibody detects endogenous levels of total CD3G. Function: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways (PubMed:2470098). In addition to this role of signal transduction in T-cell activation, CD3G pla |
Immunogen | Immunogen: A synthesized peptide derived from human CD3G Subcellular Location: Plasma Membrane Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (92%), Horse (100%), Sheep (92%), Rabbit (100%), Dog (100%) |
Other Names | [CD3 gamma; CD3-GAMMA; CD3g; CD3g antigen gamma polypeptide (TiT3 complex); CD3g antigen gamma polypeptide; CD3g molecule gamma (CD3 TCR complex); CD3g molecule gamma; CD3G_HUMAN; FLJ17620; FLJ17664; FLJ79544; FLJ94613; MGC138597; T cell antigen receptor complex gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain; T3G] |
Gene, Accession # | [CD3G], Gene ID: 917, NCBI: NP_000064.1, UniProt: P09693 |
Catalog # | MBS9608555 |
Price | $240, $280 |
Order / More Info | CD3G Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |