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Antigenic Specificity | DUSP3 |
Clone | [AT9E6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DUSP3, also known as Dual specificity protein phosphatase 3, is inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. |
Immunogen | Immunogen: Recombinant human DUSP3 (1-185aa) purified from E. coli |
Other Names | [Dual specificity protein phosphatase 3; VHR], [DUSP3; DUSP3; VHR; VHR; VHR] |
Gene, Accession # | [DUSP3], Gene ID: 1845, NCBI: NP_004081, UniProt: P51452 |
Catalog # | MBS200360 |
Price | $240, $315 |
Order / More Info | DUSP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sun H. (1998) Mol Biol. 84: 307-318.; Folander K., et al. (1995) Genomics. 23 (1): 295-296. |